The HPE DL380 Gen10, Dell R740, and Lenovo SR650 are all enterprise-class servers that are designed for a wide range of workloads. Here is a comparison of some of their key features and specifications:

HPE DL380 Gen10	Dell R740	Lenovo SR650
Supports Intel Xeon Scalable processors, with up to 28 cores per processor Supports up to two Intel Xeon Scalable processors Up to 3TB of memory and 24 DIMM slots Up to 12 LFF or 24 SFF hot-swap drive bays Multiple expansion slots, including PCIe 3.0 and OCP 3.0 mezzanine slots	Supports Intel Xeon Scalable processors, with up to 28 cores per processor Supports up to two Intel Xeon Scalable processors Up to 3TB of memory and 24 DIMM slots Up to 24 SFF or 8 LFF hot-swap drive bays Multiple expansion slots, including PCIe 3.0 and OCP 3.0 mezzanine slots	Supports Intel Xeon Scalable processors, with up to 28 cores per processor Supports up to two Intel Xeon Scalable processors Up to 3TB of memory and 24 DIMM slots Up to 8 LFF or 16 SFF hot-swap drive bays Multiple expansion slots, including PCIe 3.0 and OCP 3.0 mezzanine slots
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All three servers are highly configurable and can be tailored to meet a wide range of performance and storage needs. However, one key difference to keep in mind is that the HPE DL380 Gen10 and Dell R740 support a wider range of storage options, thanks to their greater number of hot-swap drive bays. The Lenovo SR650 has less drive bays and drive storage capacity compared to the other two.

It’s also worth noting that HPE DL380 Gen10 and Dell R740, are considered more popular in the market and are well-proven with good reputation in terms of support and compatibility with various enterprise software, and have a larger ecosystem. While Lenovo SR650 is also a good option but it’s less common in the market.

Overall, the choice between these servers will depend on the specific needs of your organization and the workloads you plan to run on them.